After you upgrade your system to Window 10, your Logitech mouse doesn’t work properly or doesn’t work at all, the problem most probably caused due to driver issues. The mouse driver might be removing, outdated, incompatible with the new system, or driver conflicts occur. Most often, you can resolve the problem by updating the drivers. You can go to to check if there is problem with Logitech Mouse driver. If there is a yellow mark next to the mouse device, the driver is not working properly.

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